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Clinical study on the efficacy and safety of epidural steroid injection in the treatment of lumbar intervertebral disc herniation related radicular pain

Clinical study on the efficacy and safety of epidural steroid injection in the treatment of lumbar intervertebral disc herniation related radicular pain

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200066273
Enrollment
Unknown
Registered
2022-11-30
Start date
2022-02-05
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

radicular pain associated with lumbar disc herniation

Interventions

group A(methylprednisolone 10mg):none
group B (methylprednisolone 20mg):none
group C (methylprednisolone 40mg):none

Sponsors

Department of Painology, General Hospital of Eastern Theater Command
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Radicular pain associated with lumbar disc herniation, 2.Aged 18-80 years, 3.MSU Classification is 1 or 2 and NRS>=4, 4.Pain persists or deteriorates<=4 weeks in this time, 5.Appropriate for epidural injection treatment under evaluation

Exclusion criteria

Exclusion criteria: 1.Severe spinal deformity, nucleus pulposus prolapse or dissociation, 2.History of lumbar surgery, 3.Local,systemic and intraspinal infection, 4.Patients with diabetes without drug control, 5.history of bleeding disorders, 6.People who suffer from allergic diseases or have a history of allergies to research drugs, 7.Patients with a history of interventional therapy within 60 days of research begin, 8.Pregnant and lactating women, 9.People with mental illness.

Design outcomes

Primary

MeasureTime frame
Numeric Rating Scale;

Secondary

MeasureTime frame
Oswestry disability index;fasting plasma glucose;Serum cortisol concentration;Serum adrenocorticotropic hormone concentration;Incidence of adverse effects;

Countries

China

Contacts

Public ContactJin Yi

General Hospital of Eastern Theater Command

kimye@vip.163.com13851516946

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026