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The role of OC pretreatment in PPOS in PCOS patients with high level of basal LH

The optimized clinical trial of PPOS regimen in PCOS patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200066265
Enrollment
Unknown
Registered
2022-11-29
Start date
2022-11-14
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic ovary syndrome

Interventions

Test group:OC pretreatment+PPOS
Control group:PPOS

Sponsors

Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 39 Years

Inclusion criteria

Inclusion criteria: 1. Patients with PCOS were diagnosed according to Rotterdam standards in 2003; 2. Basal LH >= 10IU/L; 3. Female age<40; 4. Comply with IVF-ET treatment indications.

Exclusion criteria

Exclusion criteria: 1. Patients with serious systemic diseases unsuitable for pregnancy (such as malignant tumor, congenital heart disease, systemic lupus erythematosus active period, etc.); 2. Patients with malignant tumors of reproductive tract; 3. Patients with sever uterine malformation.

Design outcomes

Primary

MeasureTime frame
Live rate of transplantation in the first cycle;

Secondary

MeasureTime frame
numbers of oocytes retrieved;Number of metaphase II oocytes;Fertilization rate;Number of fertilized oocytes;Viable embryo rate per oocyte retrieved;Cancellation rate;Clinical pregnancy rate;Implantation rate;Early miscarriage rate;Live birth rate;Gestation weeks at delivery;Mode of delivery;Newborn weight;Length of newborn;Incidence of birth defects;Pregnancy complications;Number of follicular monitoring;treatment cost;

Countries

China

Contacts

Public ContactYanping Kuang

Shanghai Ninth People’s Hospital Affiliated to Shanghai JiaoTong University School of Medicine

kuangyanp@126.com13501800828

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026