Spot
Conditions
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Men or women aged 18-60 in good health 2. There should be at least one obvious stain with ITA difference value greater than 10 from the surrounding skin, and the diameter should not be less than 3mm (it should not be freckles, nevus, etc. that are difficult to be improved by clinical application of topical preparations). 3. No allergic diseases, no allergic history of cosmetics, skin care products and other external preparations 4. No drugs affecting photosensitivity have been used recently 5. The skin of the test site should be free of birthmarks, inflammation, scars, hirsuty and other phenomena 6. Able to understand the test process, voluntarily participate in the test and sign a written informed consent
Exclusion criteria
Exclusion criteria: 1. Subjects who are pregnant or nursing, or who plan to become pregnant in the near future 2. Patients with psoriasis, eczema, atopic dermatitis, severe acne and other skin history; Or have other chronic systemic diseases 3. Oral or topical use of corticosteroid and other anti-inflammatory drugs within 1 month 4. Use of hydroquinone, salicylic acid and other products or drugs that affect skin color (such as hydroquinone preparations) within the past 2 months 5. Patients who have used retinoic acid or undergone chemical stripping, laser, pulsed light and other medical treatments in the test site within the last 3 months 6. People who cannot avoid prolonged sun exposure 7. Participants who have participated in other clinical trials within the last 2 months 8. Participants deemed unsuitable for the trial by other clinical assessments
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin color;Skin melanin;Standard image capture;Clinical evaluation; | — |
Countries
China
Contacts
Public ContactWang Xi
West China Hospital, Sichuan University
Outcome results
None listed