Low back pain
Conditions
Interventions
group1:Real HD-tDCS + ABM
group2:sham HD-tDCS + ABM
Sponsors
The Sixth Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
22 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1) Being right-handed; 2) aged 18-65 years, with a history of chronic low back pain for more than 3 months, and a mean NRS score of rest pain greater than 3 on a scale of 0-10 in the past week; 3) BDI score, non-depressed patients; 4) have not participated in psychological experiments before; 5) body mass index (BMI) should be in the normal range: 18.5 ± 27kg/m2; 6) pain-modifying medications (including antipyretics and sleeping pills) should not be taken; Female candidates should be in the middle and late follicular phase; 7) Patients with a score less than 24 on the Mini-Mental State Examination (MMSE) were excluded; 8) have normal or corrected vision and normal color vision.
Exclusion criteria
Exclusion criteria: 1) Body index > 30 kg/m2; 2) with metal and electronic implants; Known intracranial tumors and a history of craniocerebral injury; 3) intake of opioid analgesics , tetracyclic antidepressants, antiviral drugs and antipsychotics; The use of narcotic analgesics was tested in the first two weeks; Use of non-narcotic analgesics (e.g., NSAIDs) 24 hours before testing; 4) frequent headache or tinnitus and a history of alcohol or drug abuse; Confirmation or suspicion of pregnancy and lactation; 5) include evidence of spinal cord defects, any history of back/brain surgery; 6) diagnosed acute or chronic mental illness or other mental illness; Severe neurological disorders; History of epilepsy, family history of epilepsy; A 15-minute history of loss of consciousness; 7) pregnancy, any open wounds on the scalp and/or face; 8) hearing or vision impairment; Illiterate; 9) have any contraindications to tDCS; 10) drug dependence/abuse or presence of a degenerative disease (e.g., Alzheimer's disease); 11) consume > 8 units of caffeine per day (maximum one cup of caffeine on the test day); Smokers daily > 5 pieces; 12) severe depression with a score greater than 35 on the Beck Depression Inventory (BDI).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Alpha Oscillations; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain-threshold; | — |
Countries
China
Contacts
Public ContactYuling Wang
The Sixth Affiliated Hospital of Sun Yat-sen University
Outcome results
None listed