Postoperative pain management after open cardiac surgery
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age >18 years; 2. Elective open heart surgery through midsternal incision is planned; 3. ASAII-III Grade; 4. Volunteer to participate in this study and sign the informed consent
Exclusion criteria
Exclusion criteria: 1, BMI > 35 kg/m2; 2. The puncture site is complicated with infected persons; 3. History of alcoholism, anesthesia or illicit drug abuse (taking opioids for more than 3 months or oral morphine equivalent >15mg/ day for a month); 4. Long-term use of stress dose steroids before surgery; 5, allergic to amide anesthetics; 6. Patients with peripheral nerve disease or blood system disease; 7. The combination of vital organ dysfunction, severe arrhythmia and low cardiac output requires positive inotropic drugs or intra-aortic balloon counterpulsation supporters, and the preoperative EF value is less than 30%; 8. Combined with mental disorders or cognitive dysfunction, unable to make independent judgments; 9.pregnancy 10. Allergic to tramadol hydrochloride and morphine hydrochloride
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Maximum pain score; | — |
Secondary
| Measure | Time frame |
|---|---|
| dosage of Tramadol;dosage of Morphine;Interleukin - 6;C reactive protein;Neutrophil-lymphocyte ratio;White blood cell;The time to extubation;Length of stay in ICU;length of stay;Incidence of CPSI block-related complications;Dosage of Remifentanil; | — |
Countries
China
Contacts
Fuling Hospital Affiliated to Chongqing University