Hypoproteinemia
Conditions
Interventions
Experimental group:Whey Protein Isolated Solid Beverages (containing 18g protein/bag, 20g/bag),take orally for 21 days
Control group:Whey Protein Isolated Solid Beverages (containing 18g protein/bag, 20g/bag),take orally for 21 days
Positive Control group:Protein Hydrolysate Oral solution Solution (containing 14.7g protein/bottle, 100mL/bottle),take orally for 25 days
Sponsors
Department of Pharmacy, Jincheng General Hospital
Eligibility
Sex/Gender
All
Age
20 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Patients aged from 20 to 75 years (including borderline values), male or female; (2) Plasma total protein = 60 g/L or plasma albumin 28-35 g/L; (3) Hemoglobin (Hb) > 90 g/L; (4) BMI > 16 kg/m2; (5) Patients has no subjective weight loss >10 % in the recent 6 months; (6) Patients has no cognitive impairment and positive cooperation in completing the observation; (7) Patients or their guardians voluntarily signed the informed consent.
Exclusion criteria
Exclusion criteria: (1) Liver and kidney function test results showed ALT, AST > 2 times the upper limit of normal values, or Cr > 1.5 times the upper limit of normal values (refer to the normal range of laboratory tests);(2) Those who are allergic to animal protein (egg protein); (3) Patients with chronic anemia, Hb <60g/L; patients with concurrent metabolic diseases; (4) Patients with clear contraindications to enteral nutrition; suspected or confirmed history of substance abuse; (5)Patients with comorbid other psychiatric disorders and poor compliance. (6) Patients have large amounts of exudative pleural/ ascites, or large amounts of urinary protein due to abnormal renal function . (7) Patients who are at risk of drug combination or adverse reactions between the drugs used and the clinical drug hydrolyzed protein oral solution. (8) Patients who have participated in this clinical trial within the last two months. (9) Patients deemed unsuitable for clinical trials by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood biochemical indicators; | — |
Secondary
| Measure | Time frame |
|---|---|
| Routine blood indicators;Serological indicators;Phenotypic observation; | — |
Countries
China
Contacts
Public ContactZhang Lu?Ji Ligang
China National Research Institute of Food and Fermentation Industries;Jincheng General Hospital;rict, Beijing,China
Outcome results
None listed