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Therapeutic effect and brain mechanism of tDCS for negative symptoms of schizophrenia

Therapeutic effect and brain mechanism of tDCS for negative symptoms of schizophrenia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200066217
Enrollment
Unknown
Registered
2022-11-28
Start date
2022-12-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

schizophrenia

Interventions

Experimental group:Transcranial direct current therapy

Sponsors

Zhenjiang Mental Health Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1. Diagnosed as schizophrenia according to ICD-10, with a history of >=1 year, 2. Age 18-65, 3. Right-handed, 4. After taking a fixed dose and type of antipsychotics for more than 12 weeks, significant negative symptoms persist, that is, SNASS score >=20 5. No physical therapy such as rTMS, transcranial direct current, or electroshock has been performed in the past six months; 6. The patient's guardian or other family members gave informed consent to the study and signed the informed consent form.

Exclusion criteria

Exclusion criteria: Exclusion criteria: 1. History of nervous system, past history of craniocerebral trauma, space-occupying disease, encephalitis and other organic lesions; 2. A history of alcohol, drug, or other psychoactive substance abuse 3. Patients with bipolar disorder, depression, or other psychiatric disorders 4. Suffer from serious internal diseases, including cardiovascular system, urinary system, respiratory system and digestive system, and other serious physical diseases;5. Patients who have recently planned to become pregnant, are pregnant or breastfeeding 6. The previous treatment of tDCS was not effective.

Countries

China

Contacts

Public ContactSun Jingjing
599308249@qq.com+86 17696031977

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026