Effect of limb remote ischemic postconditioning on hepatic ischemia reperfusion injury in patients undergoing hepatectomy

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200066202

Enrollment

Unknown

Registered

2022-11-28

Start date

2022-12-01

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hepatectomy

Interventions

Limb remote ischemic postconditioning group:Inflate and pressurize the left lower limb blood pressure cuff to 200mmHg for 5min, and then deflate for 5min

Control group:The left lower limb adopts the same technique, but the cuff is not inflated

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. patients and their families signed informed consent, surgery and anesthesia consent ; 2. ASA grade I-III ; 3. Good cognitive function, no surgical contraindications ; 4. Patients aged 18-75 years identified for hepatectomy.

Exclusion criteria

Exclusion criteria: 1. Local limb infection ; 2. Severe renal insufficiency ; ( glomerular filtration rate < 30ml / min / 1.73m2 ) ; 3. Severe liver dysfunction ; ( Child-Pugh C ) ; 4. patients with repeated liver resection ; 5. Peripheral vascular disease ; 6. a history of cryosurgery, radiofrequency ablation or chemotherapy ; 7. Uncontrolled diabetes and sepsis.

Design outcomes

Primary

Measure	Time frame
Alanine aminotransferase;Aspartate aminotransferase;Total bilirubin;	—

Countries

China

Contacts

Public ContactWeidong Liang

First Affiliated Hospital of Gannan Medical College

lwd0929@gmu.edu.cn15970122157

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026