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Randomized, controlled clinical study on the efficacy and safety of Lianhua Qingke Tablet in the treatment of novel coronavirus pneumonia patients with basic diseases

Randomized, controlled clinical study on the efficacy and safety of Lianhua Qingke Tablet in the treatment of novel coronavirus pneumonia patients with basic diseases

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200066183
Enrollment
Unknown
Registered
2022-11-26
Start date
2022-11-25
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19

Interventions

Drug group:Basic treatment+Lianhua Qingke tablet, 4 tablets/time, 3 times/day
Control grou:Basic treatment

Sponsors

Hebei Chest Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. It meets the diagnostic criteria for novel coronavirus pneumonia; 2. Age >= 18 years; 3. The first nucleic acid positive time is within 72h; 4. Cough symptoms at admission; 5. The patient or family member knows the research content and voluntarily signs the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Severe cardiac insufficiency, liver and kidney failure; 2. The expected survival time of patients is less than 14 days due to basic diseases, such as poor control of malignant tumors, cardiac arrest in the past 30 days, etc; 3. Patients with serious mental illness; 4. Pregnant or preparing for pregnancy, or unable to take effective contraceptive measures; 5. Allergies to the active ingredients of the test drug or its excipients; 6. Participated in clinical intervention test in recent 3 months; 7. Subjects who the researcher thinks are not suitable to participate in this experiment.

Design outcomes

Primary

MeasureTime frame
The disappearance rate and median time of clinical symptoms (cough, expectoration, fatigue, sore throat, dry throat, fever, nasal congestion, runny nose, etc.);

Secondary

MeasureTime frame
Disappearance rate of cough and other single clinical symptoms;Changes of alveolar injury markers, inflammatory factors, antibody content and antibody typing in blood components of the two groups;Proportion of the two groups converted to heavy/dangerous heavy;Mortality rate of two groups of patients with novel coronavirus pneumonia during treatment;Nucleic acid negative rate and length of hospitalization in the two groups;Changes of CT/X-ray imaging examination of chest in both groups;

Countries

China

Contacts

Public ContactShucai Wu

Hebei Chest Hospital

xkyykjc@163.com+86 311 8691 1140

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026