minimal hepatic encephalopathy
Conditions
Interventions
Propofol group:propofol drug
remimazolam group:remimazolam drug
sevoflurane group:sevoflurane drug
Sponsors
Liaocheng People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: patients undergoing esophagogastric varices and / or sclerotherapy in the center of digestive endoscopy in our hospital. Patients should have a complete medical history, physical examination, chest X-ray, and electrocardiogram examination, as well as complete blood routine, liver and kidney function, and virus screening and abdominal ultrasound examination. Patients aged 18 to 80 years; patients with cirrhosis with endoscopic descending EVL and / or EVS; esophageal varicose pattern grade G ~G; liver function Child-Pugh class A, B, or C; patients who agreed to receive endoscopic treatment and signed informed consent.
Exclusion criteria
Exclusion criteria: The American Association of Anesthesiologists (American Society of Anesthesiologists, ASA) grades IV or V; alcohol, opioid, or sedative-hypnotic addiction; clinically detectable hepatic encephalopathy, psychiatric, psychiatric, or active neurological disorders; neurological diseases such as Alzheimer's or Parkinson's; perioperative hemorrhagic shock; known allergy to egg products, tofu, soy, propofol, or benzodiazepines.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NCT-A DST; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of Recovery-40 Questionnaire,Qo R-40;spontaneous breathing time;awaking time;extubation time;Steward MOAA/S;Postoperative adverse effects;Pittsburgh Sleep Quality Index (PSQI);health-related quality of life (HRQoL); | — |
Countries
CHINA
Contacts
Public ContactFu Shi
Liaocheng People's Hospital
Outcome results
None listed