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Effects of different sedative drug administration methods on sedative effect and postoperative restlessness in children

Effects of different sedative drug administration methods on sedative effect and postoperative restlessness in children

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200066149
Enrollment
Unknown
Registered
2022-11-25
Start date
2022-11-28
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oblique inguinal hernia

Interventions

midazolam group:Take 0.8mg/kg oral preparation of midazolam 30 minutes before entering the operating room
dexmedetomidine group:2.0 ug/kg Dexmedetomidine was dropped intranasally 30 minutes before admission to the operating room

Sponsors

Fujian Medical University Affiliated First Quanzhou Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 6 Years

Inclusion criteria

Inclusion criteria: The participants in this study were 2 to 5 years of age, no gender limitation, American Society of Anesthesiologists class 1 or 2, and were scheduled to undergo laparoscopic high ligation of inguinal oblique hernia sac under general anesthesia from November 2022 to August 2023.

Exclusion criteria

Exclusion criteria: Patients were excluded from the study if they had a known history or clinical evidence of chronic obstructive pulmonary disease or respiratory insufficiency based on pre-operative medications or a pulmonary function test. Patients were also excluded if they had a history of renal or hepatic dysfunction, neurological diseases, cardiovascular diseases, sleep apnea syndrome, recent symptoms of an upper respiratory infection, or if they had taken sedatives, analgesics, or cardiovascular medications in the last month.

Design outcomes

Primary

MeasureTime frame
Funk score /Cm-YPAS score;PAED score;FLACC score;

Secondary

MeasureTime frame
the operation time;heart rate;Oxygen saturation;the operation time;the wake up time;

Countries

China

Contacts

Public ContactJingyang Zeng

Fujian Medical University Affiliated First Quanzhou Hospital

serendipity1221@126.com+86 138 6072 8258

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026