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A prospective study of esketamine combined with propofol basic anesthesia in brachial plexus block in children

A prospective study of esketamine combined with propofol basic anesthesia in brachial plexus block in children

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200066145
Enrollment
Unknown
Registered
2022-11-25
Start date
2022-11-25
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Upper extremity fracture

Interventions

Test group:propofol combined with esketamine

Sponsors

Shenzhen Children's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 6 Years

Inclusion criteria

Inclusion criteria: 1. Children with unilateral humeral or radial fractures requiring closed reduction and internal fixation; 2. ASA grades I-II; 3. Aged 3 to 6 years old, no limit on gender; 4. BMI between 18~30kg/m^2.

Exclusion criteria

Exclusion criteria: 1. Allergic to ropivacaine or(and)other drugs; 2. Infection in operation area; 3. Elevated blood pressure or(and)intraocular pressure or(and)intracranial pressure; 4. The time of operation exceeds two hours; 5. Cardio-pulmonary dysfunction; 6. Cognitive dysfunction or(and)epileptic children; 7. Signing name on informed consent document; 8. Taking sedative drugs over a long period of time; 9. Enhanced muscle tone.

Design outcomes

Primary

MeasureTime frame
Adverse events of airway in anesthesia or operation;

Secondary

MeasureTime frame
Awakening time;The dose of intravenous anesthetic drug;The grade of anesthesia effect;Postoperative complications;Systolic blood pressure;Oxygen saturation;Diastolic blood pressure;Average arterial blood pressure;Heart rate;Transcutsneous carbon dioxide partial pressure;Breathing rate;

Countries

China

Contacts

Public ContactFANG CHEN

Shenzhen Children's Hospital

18938690929@163.com+86 189 3869 0929

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026