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Effects of intranasal dexmedetomidine on postoperative agitation in pediatric

Effects of different doses of intranasal dexmedetomidine on postoperative agitation in pediatric undergoing minor surgery

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200066136
Enrollment
Unknown
Registered
2022-11-25
Start date
2022-12-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative agitation

Interventions

Group D1:Dexmedetomidine 1ug/kg
Group D2:Dexmedetomidine 1.5ug/kg
Group NS:Equivalent normal saline

Sponsors

The First Hospital Of Jilin University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 6 Years

Inclusion criteria

Inclusion criteria: 1. Children undergoing laparoscopic hernia sac or processus vaginalis high ligation with general anesthesia; 2. Aged 6 months to 6 years; 3. ASA I.

Exclusion criteria

Exclusion criteria: 1. Respiratory diseases such as upper respiratory tract infection and asthma; 2. Cardiac insufficiency such as congenital heart diseases and congenital dysplasia; 3. Severe liver or kidney disease; 4. BMI >=30; 5. Allergy to dexmedetomidine; 6. Parental refusal.

Design outcomes

Primary

MeasureTime frame
Emergence Agitation score;Ramsay sedation score;

Secondary

MeasureTime frame
Duration of surgery;extubation time (from the induction of anesthesia to the removal of tracheal tube);recovery time (from the induction of anesthesia to the time of leaving PACU);

Countries

China

Contacts

Public ContactDong Su

The First Hospital Of Jilin University

dongsu327@sina.com+86 135 7892 3360

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026