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Effects of inverse ventilation combined with PCV-VG mode on respiratory mechanics and lung injury in obese patients with laparoscopic gastric volume reduction

Effects of inverse ventilation combined with PCV-VG mode on respiratory mechanics and lung injury in obese patients with laparoscopic gastric volume reduction - Effects of inverse ventilation combined with PCV-VG mode on respiratory mechanics and lung injury in obese patients with laparoscopic gastric volume reduction

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200066124
Enrollment
Unknown
Registered
2022-11-24
Start date
2021-12-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Metabolic syndrome

Interventions

Inverse ventilation group:The I:E ratio is 2:1
regular ventilation group:The I:E ratio is 1:2

Sponsors

Inner Mongolia Autonomous Region People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Age 18 to 45 years; 2. Elective surgery; 3. ASA grade I to II, BMI >30 kg/m^2; 4. No preoperative cardiopulmonary complications; 5. No abnormalities in liver and kidney function; 6. Mechanical ventilation time 2 to 3 h.

Exclusion criteria

Exclusion criteria: 1. History of exposure to anesthesia within 1 year; 2. Have a history of chest trauma and surgery; 3. Hypercapnia has been present before surgery; 4. Intraoperative airway peak pressure > 30cmH2O; 5. Those who refuse to participate in the experiment and do not sign the informed consent form.

Design outcomes

Primary

MeasureTime frame
SP-A;CC16;Dynamic lung compliance;Airway peak pressure;mean airway pressure;Drive pressure;Arterial blood carbon dioxide partial pressure;Arterial partial pressure of oxygen;Oxygenation index;

Countries

China

Contacts

Public ContactZhihui Zhao

Inner Mongolia Autonomous Region People's Hospital

1729016277@qq.com+86 180 0471 2242

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026