obesity, diabetes
Conditions
Interventions
NA:NA
Sponsors
Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patients were eligible if they: 1. Fulfilled the criterion for overweight or obesity (BMI >= 24kg/m^2); waist circumference >= 90cm for adult males, waist circumference >= 90cm for adult females, or waist-hip ratio > 1.0. 2. Aged over 18 years old ; 3. Without receiving any medications that influenced glucose and lipid metabolism or weight loss surgery; 4. Finished venous blood collection and MRI examination.
Exclusion criteria
Exclusion criteria: Patients were deemed not eligible for the study if they: 1. Diagnosed as secondary obesity, such as hypothyroidism, Cushing syndrome, polycystic ovary syndrome (PCOS); 2. Severe cardiovascular and cerebrovascular diseases and rheumatic immune disease; 3. Severe metabolism diseases, such as diabetic ketoacidosis and hyperosmolar hyperglycemic state; 4. Advanced malignant neoplasm; 5. Previous use of glucocorticoids, antibiotics, antidiabetic agents, antidepressant or antianxiety medications that influenced glucose and lipid metabolism; 6. Did not finish venous blood collection; 7. Did not finish MRI examination; 8. Had other conditions that the researchers deemed inappropriate for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| visceral adipose tissue;blood glucose;insulin;C-Peptide;glycated hemoglobin;fat content in skeletal muscle; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood lipid;inflammatory factor(IL-2, IL-6, IL- 8, IL-10, TNF-a); | — |
Countries
China
Contacts
Public ContactJing Ma
Outcome results
None listed