atypical pathogens, resistant gram-negative bacteria, tuberculosis infection
Conditions
Interventions
Quinolone treatment group:N/A
Non quinolone drug treatment group:N/A
Sponsors
Pediatric Intensive Care Unit, Beijing Children's Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
No minimum to 18 Years
Inclusion criteria
Inclusion criteria: 1. Children with 29d-18y atypical pathogens, drug-resistant Gram-negative bacteria and tuberculosis infection who were intravenously or orally administered with quinolones (ciprofloxacin 10 mg/kg/d, Q8h; levofloxacin 10 mg/kg/d, QD, maximum 14 days, maximum dose no more than 500 mg; moxifloxacin 10 mg/kg/d, QD, maximum 14 days, maximum dose no more than 400 mg) in the Department of Intensive Care Medicine and the Department of Respiratory Medicine II of Beijing Children's Hospital; 2. Administration time >= 3 days; 3. Signing the informed consent for off-label use.
Exclusion criteria
Exclusion criteria: no
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| X-ray of both knees;electrocardiogram;echocardiography;blood concentration;blood concentration; | — |
Countries
China
Contacts
Public ContactQian Suyun
Pediatric Intensive Care Unit, Beijing Children's Hospital, Capital Medical University
Outcome results
None listed