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Assessment of lumbar vertebral bone quality with vertebral bone quality score and hounsfield units value

Assessment of lumbar vertebral bone quality with vertebral bone quality score and hounsfield units value

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200066108
Enrollment
Unknown
Registered
2022-11-24
Start date
2022-12-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoporosis

Interventions

Gold Standard:Bone mineral density measured by qCT and or EDXA or patients with fragility fracture.
Index test:VBQ score, HU value, qCT measurement value, and markers of bone metabolism (25 hydroxyvitamin D, type 1 procollagen N-terminal propeptide (P1NP), type 1 collagen C-terminal peptide (CTX), s

Sponsors

Yan'an Hospital Affiliated to Kunming Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. The patient received qCT, CT plain scan and MRI plain scan of lumbar spine within one month; 2. Older than 18 years.

Exclusion criteria

Exclusion criteria: 1. Previous lumbar fusion; 2. Complications, such as diffuse idiopathic hyperosteogeny, ankylosing spondylitis, lumbar infection, lumbar tumor and lumbar trauma; 3. Patients with measurement difficulties due to schmorl nodules, local osteosclerosis and interference artifacts; 4. Examination received by the patient.

Design outcomes

Primary

MeasureTime frame
VBQ score;HU value;qCT measurement value;

Secondary

MeasureTime frame
25 hydroxyvitamin D;type 1 procollagen N-terminal propeptide (P1NP);type 1 collagen C-terminal peptide (CTX);serum osteocalcin (BGP);calcitonin (CT);parathyroid hormone (PTH);

Countries

China

Contacts

Public ContactXingxiao Pu

Yan'an Hospital Affiliated to Kunming Medical University

2801124519@qq.com+86 15734063904

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026