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Discussion on clinical symptoms and immune regulatory effects of combined product of compound probiotics freeze-dried powder and zinc compound B nutrient agent on children with food allergy

Discussion on clinical symptoms and immune regulatory effects of combined product of compound probiotics freeze-dried powder and zinc compound B nutrient agent on children with food allergy

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200066105
Enrollment
Unknown
Registered
2022-11-24
Start date
2022-12-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Food allergy

Interventions

the experiment group:compound probiotics freeze-dried powder and zinc compound B nutrient agent+Hydrolyzed Protein Formula Milk
treatment group:Hydrolyzed Protein Formula Milk

Sponsors

Wuxi Ninth hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 6 Years

Inclusion criteria

Inclusion criteria: 1. Children with food allergy aged between 0-6 ; 2. lgE above 100 IU/ mL; 3. Symptoms > 8mm in the skin prick test; 4. Experimental group took probiotics, zinc compound B nutrient agent, and hydrolyzed protein formula and milk for 6 months, and was seen for follow-up for 6 months after cutting off, to evaluate whether the lactic acid bacteria can promote tolerance; 5. To evaluate the influence of hydrolyzed protein formula milk, the control group took the hydrolyzed formula for 6 months only and was seen for follow-up for 6 months after cutting off.

Exclusion criteria

Exclusion criteria: 1. With non allergenic disease or chronic disease; 2. With severe food allergy reactions, such as hypotensionprostrationhypoxia? shock etc.; 3. With ß-blockers?cardiovascular disease or asthma not well controlled; 4. With indwelling catheters?esophagostomy?gastronomy etc.; 5. With taking other probiotic products; 6. Allergic to saccharides such as polydextrose?fructooligosaccharide(FOS), glucose(subsidiary material).

Design outcomes

Primary

MeasureTime frame
Serum IgE or IgG4;skin prick test;Zn;Vb2;

Countries

China

Contacts

Public ContactMingxing Ren

Wuxi Ninth hospital

Swb771228@163.com+86 13806186700

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026