obstructive sleep apnea
Conditions
Interventions
Routine anesthesia group:Anesthesia with opioid
Opioid free anesthesia group:Anesthesia without opioid
Sponsors
Zhongshan Hospital of Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Participants of American Society of Anesthesiologists (ASA) I-II must be aged between 18 to 80 and be high risk population of OSA patients assessed by STOP-BANG scale, undergoing open hepatectomy under combined general and epidural anesthesia. Participants will be required to provide written, informed consent to be eligible to participate in this trial.
Exclusion criteria
Exclusion criteria: The exclusion criteria will include neuropsychiatric diseases, long-term use of psychotropic and analgesics, alcoholism, consciousness disorder, language dysfunction, communication disorder, severe cardiopulmonary, liver and kidney dysfunction, allergic to test drugs, and postoperative admission to intensive care unit (ICU).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| AHI;4%ODI; | — |
Secondary
| Measure | Time frame |
|---|---|
| sleep;pain;postoperative recovery;exosomes; | — |
Countries
China
Contacts
Public ContactXiaoguang Zhang
Zhongshan Hospital of Fudan University
Outcome results
None listed