Analgesic effect of nerve block anesthesia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients who underwent laparoscopic colorectal cancer surgery in our hospital 2. Age 18-80 years old, gender is not limited 3. ASA Grade I~II 4. Those who have a clear understanding, voluntarily participate in the study, and sign an informed consent form
Exclusion criteria
Exclusion criteria: 1.Peripheral nerve block contraindications 2. Those who are allergic to local anesthetic drugs 3. Drug abusers (opioids, cortisols) 4. BMI> 35kg/m2 and BMI<18kg/m2 5. Any known heart failure, liver failure, chronic kidney disease 6. Endocrine diseases 7. Those who have undergone secondary open surgery 8. Patients with abnormal coagulation function and severe anemia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Remifentanil dosage; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in vital signs (heart rate, systolic/diastolic pressure, mean arterial pressure, BIS, and pain index) at various time points during surgery (baseline entry, establishment of pneumoperitoneum, 15 minutes after pneumotheta, 30 minutes after pneumotheta, 45 minutes after pneumoperitoneum, 60 minutes after pneumoperitoneum, op;Pain scores of 0h, 6h, 12h, 24h after the end of surgery;Postoperative recovery (nausea and vomiting, time to get out of bed, time to gas, length of hospital stay, adverse events, etc.).;White blood cell count, neutrophil count and its proportion, urea nitrogen value, creatinine value; | — |
Countries
china
Contacts
QILU HOSPITAL OF SHANDONG UNIVERSITY