Anesthesia induction
Conditions
Interventions
propofol group:propofol
Sponsors
Jiangxi Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients older than 60 years old, 2. ASA grading I~III., 3. Fasting = 8h, drinking = 2h, 4. Elective surgical treatment.
Exclusion criteria
Exclusion criteria: 1, cyclopofol or propofol allergy, 2. Severe cardiovascular and cerebrovascular diseases (such as history of heart failure, coronary heart disease), 3. Patients with severe hypertension (hypertension grade 3 blood pressure=180/110mmHg), 4. Psychiatric and neurological diseases (such as Alzheimer's disease, cerebral infarction, cerebral trauma and cerebral hemorrhage, intracranial mass), 5. Long-term use of sedatives or antidepressants, inability to communicate or cooperate, 6.Hepatic and renal insufficiency.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of anesthesia induction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Injection pain;the time BIS dropped to 60;the time BIS dropped to 60;the time for disappearance of the eyelash reflex;Changes in BIS and changes in blood pressure and heart rate within 10 minutes of injecting the study drug;Changes in blood pressure and heart rate immediately before laryngoscopy placement, immediately after successful intubation, and 1 min after successful intubation;Incidence of adverse events (swallowing action, choking, body movements, hypotension, hypertension, tachycardia, bradycardia);The number of times the drug is added;The number of times the vasoactive drug is used; | — |
Countries
China
Contacts
Public Contactheguo luo
Jiangxi Provincial People's Hospital
Outcome results
None listed