atrial fibrillation
Conditions
Interventions
Nonvalvular atrial fibrillation with heart failure group:No
Nonvalvular atrial fibrillation without heart failure group:No
Sponsors
Su Hao
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1.Be at least 18 years old; 2.It meets the diagnostic criteria for symptomatic and non-valvular atrial fibrillation in the 2020 GUIDELINES for the Diagnosis and Management of ESC Atrial fibrillation ; 3.It meets the diagnostic criteria for heart failure in the ESC Guidelines for the Diagnosis and Treatment of Acute and Chronic Heart Failure, 2021; 4.Patients who plan to receive edoxaban for drug anticoagulation 5.Voluntarily signed the informed consent form approved by the ethics committee
Exclusion criteria
Exclusion criteria: 1.Congenital heart disease, valvular heart disease, angina pectoris, myocardial infarction, myocarditis, cardiomyopathy, pulmonary heart disease, severe infection, autoimmune diseases, hematological diseases, malignant tumors; 2.At the same time, other bradyarrhythmias, such as atrioventricular block, pathological sinus syndrome, etc., and the corresponding clinical symptoms; 3.NYHA New York Cardiac function grade ? or above, or left ventricular ejection fraction =35% according to cardiac color doppler echocardiography 4.Serious neurological diseases (neurological infections, etc.), mental disorders (including drug abuse, chronic alcoholism, etc.) 5.Severe liver dysfunction (AST or ALT >3 times the upper limit of normal) or renal dysfunction (SCr >3.5mg/dl or CCr <30ml/min) 6.Other cases with contraindications to edoxaban
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CHA2DS2-VASc score;HAS-BLED score;Transthoracic Doppler echocardiography; | — |
Countries
China
Contacts
Public ContactSu Hao
South Area of Anhui Provincial Hospital
Outcome results
None listed