Coronary artery disease
Conditions
Interventions
Grouping based on different stages of coronary artery disease:None
Sponsors
The Second Affiliated Hospital of Kunming Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Inclusive criteria for patients with coronary heart disease who intend to receive coronary angiography (CAG) or hospitalized patients suspected of coronary heart disease due to chest pain, dyspnea or abnormal electrocardiogram: ? Coronary angiography will be performed; ?Age = 18 years but =80 years. ?Sign the informed consent form. 2. Inclusive criteria for patients with new onset acute ST-segment elevation myocardial infarction (STEMI) who have received successful reperfusion therapy by percutaneous coronary intervention(PCI). ? Age = 18 years old, but < 80 years old; ? All patients with new STEMI (STEMI was symptomatic until admission < 12 hours) have received successful reperfusion therapy by percutaneous coronary intervention. ?Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Exlusion criteria for patients with coronary heart disease who intend to receive coronary angiography (CAG) or hospitalized patients suspected of coronary heart disease due to chest pain, dyspnea or abnormal electrocardiogram: ?Previous myocardial infarction, coronary stent or coronary artery bypass grafting; ?Chronic pulmonary heart disease, severe valvular heart disease, heart failure with LVEF of less than 50 percent, severe arrhythmia; rheumatic heart disease; organic heart disease such as congenital heart disease or cardiomyopathy; ?Chronic infections or inflammatory diseases, such as rheumatoid arthritis, systemic lupus erythematosus and sclerosis; ? Malignant neoplasms; serious liver or kidney diseases, thyroid disorders, hematological disorders and pregnancy; ?Drugs use of (such as immunosuppressants, hormones, etc.) patients with a history of depression or other mental disorders or patients taking antidepressants or psychotropic drugs that may affect the results of trials 2.Exlusion criteria for patients with new onset acute ST-segment elevation myocardial infarction (STEMI) who have received successful reperfusion therapy by percutaneous coronary intervention(PCI). ?Patients with a history of myocardial infarction, a history of PCI, a history of coronary artery bypass graft, ?advanced heart failure (Killip class = II), a history of significant mitral regurgitation (MR) secondary to papillary muscle rupture, ?Chronic pulmonary heart disease, severe valvular heart disease, severe arrhythmia; rheumatic heart disease; organic heart disease such as congenital heart disease or cardiomyopathy; ?Chronic infections or inflammatory diseases, such as rheumatoid arthritis, systemic lupus erythematosus and sclerosis; ?Malignant neoplasms; serious liver or kidney diseases, thyroid disorders, hematological disorders and pregnancy; ?Patients who are taking drugs (such as immunosuppressants, hormones, etc.) that affect the results of the trial, patients who have a history of depression or other mental disorders, or patients who are taking antidepressants or psychotropic drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brain-derived neurotrophic factor;Precursor brain-derived neurotrophic factor;Gensini score;TIMI frame count;Echocardiography; | — |
Countries
China
Contacts
Public ContactZhang Hongshan
The Second Affiliated Hospital of Kunming Medical University
Outcome results
None listed