Chronic hepatitis B
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.All subjects (patients) received or will receive liver biopsy.2.Age and gender are not limited.3.ALT is continuously normal.4. HBV DNA >30 IU/ml.5.No antiviral treatment before liver biopsy.
Exclusion criteria
Exclusion criteria: 1.Pregnant and lactating women.2.Inability to cooperate in completing research or poor compliance.3.Co-infected with HAV, HCV, HDV, HEV.4.Complicated with severe circulatory, nervous and immune system diseases.5.Autoimmune, alcoholic, drug - induced liver disease and other liver diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood biochemical indexes;Liver histopathological changes;Abdominal ultrasound examination;Liver stiffness;Blood routine examination; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serological markers of hepatic fibrosis; | — |
Countries
China
Contacts
Ningbo No. 2 Hospital