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Study on the early warning of disease progression of hepatitis B

Infectious Diseases

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200066028
Enrollment
Unknown
Registered
2022-11-22
Start date
2022-11-22
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic hepatitis B

Interventions

Group ALT I :N/A
Group ALT II :N/A
Group ALT ?:N/A
Group G I:N/A
Group G ?:N/A
Group S I:N/A
Group S ?:N/A
Group GS I:N/A
Group GS II:N/A

Sponsors

Ningbo No. 2 Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.All subjects (patients) received or will receive liver biopsy.2.Age and gender are not limited.3.ALT is continuously normal.4. HBV DNA >30 IU/ml.5.No antiviral treatment before liver biopsy.

Exclusion criteria

Exclusion criteria: 1.Pregnant and lactating women.2.Inability to cooperate in completing research or poor compliance.3.Co-infected with HAV, HCV, HDV, HEV.4.Complicated with severe circulatory, nervous and immune system diseases.5.Autoimmune, alcoholic, drug - induced liver disease and other liver diseases.

Design outcomes

Primary

MeasureTime frame
Blood biochemical indexes;Liver histopathological changes;Abdominal ultrasound examination;Liver stiffness;Blood routine examination;

Secondary

MeasureTime frame
Serological markers of hepatic fibrosis;

Countries

China

Contacts

Public ContactAirong Hu

Ningbo No. 2 Hospital

huairong6666@126.com13968369377

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026