postprandial discomfort syndrome
Conditions
Interventions
Sham acupuncture group:sham acupuncture
local-acupoint acupuncture group:local-acupoint acupuncture
distal-acupoint acupuncture group:distal-acupoint acupuncture
Sponsors
School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. PDS subtype patients with functional dyspepsia, aged 18-65 years (including 18 years, excluding 65 years), meeting Rome IV diagnostic criteria, male or female; 2. Body mass index within normal range (19 <= BMI < 24); 3. Patients over 35 years old should provide a normal gastroscopy report; 4. After treatment with at least two conventional drugs, the symptoms persist for at least 6 months without significant improvement; 5. No history of acupuncture treatment in the past month; 6. Right-handed; 7. Speechless and intellectually disabled, able to answer and complete the questionnaire smoothly; 8. Have not participated in other studies in the past 2 months; 9. Sign the informed consent. Inclusion criteria for healthy subjects: 1. Healthy subjects, male or female, aged 18-65 (inclusive), with body mass index within normal range (19 <= BMI < 24), and no history of early satiety and post meal discomfort; 2. No bad habits such as smoking and alcohol; 3. After the physical examination, it is confirmed that there is no major organ disease, and the liver and kidney functions are normal; 4. Right-handed hand; 5. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Symptoms of dyspepsia caused by any serious or malignant disease, such as liver cirrhosis, heart failure or gastrointestinal tumors; 2. Gastrointestinal tract related surgery; 3. Take drugs that may affect indigestion, such as antisecretory drugs, antacids, promoters, non-steroidal anti-inflammatory drugs, and antidepressants, within one month of participating in the trial; 4. Severe coagulation disorders; 5. Drug or alcohol abuse; 6. Pregnancy or lactation; 7. Have received acupuncture for gastrointestinal diseases in the past 6 months; 8. Contraindications of magnetic resonance examination: patients with pacemakers, nerve stimulators, artificial metal heart valves, etc.; With aneurysm clips (except non-paramagnetic, such as titanium alloy); There are metal foreign bodies in the eye, inner ear implantation, metal prosthesis, metal prosthesis, metal joint, ferromagnetic foreign bodies in the body; Patients with severe high fever.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effective response rate;Symptom elimination rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Midupper abdominal tenderness threshold;Bilateral forearm tenderness threshold;Von Frey tactile test;Nipin's dyspepsia index;Simplified McGill Pain Scale;Sensitivity of pain;Hamilton Depression Scale;Hamilton Anxiety Scale;Blinding and credibility evaluation;Brain-spinal cord magenetic resonance imaging;Effective response rate;Symptom elimination rate; | — |
Countries
China
Contacts
Public ContactCunzhi Liu
School of Acupuncture and Tuina, Beijing University of Chinese Medicine
Outcome results
None listed