Renal inflammation and fibrosis
Conditions
Interventions
Gold Standard:Renal puncture biopsy
Index test:18F-FAPI PET/CT examination
Sponsors
Sichuan Academy of Medical Sciences, Sichuan Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
10 Years to 60 Years
Inclusion criteria
Inclusion criteria: Clinical diagnosis of renal inflammation or fibrosis disease.
Exclusion criteria
Exclusion criteria: 1. Hypertension that is difficult to control with medication, and systolic blood pressure exceeding 160 mmHg; 2. Renal biopsy cannot be performed for severe exclotting disease; 3. Complicated with chronic liver disease, myocardial infarction, stroke, and malignant tumor; 4. Unable to cooperate with renal puncture biopsy due to language communication or other problems; 5. Female patients who are pregnant (or attempting to become pregnant within six months), breastfeeding, or unwilling to use contraception; 6. Abnormal cardiopulmonary function or mental state, unable to tolerate prone lying for 20 minutes; 7. Alcohol allergy; 8. Patients with significant decrease in urine volume due to disease; 9. Refusal to sign an informed consent form or inability or unwillingness to comply with the investigator-approved protocol; 10. Other circumstances deemed inappropriate by the investigator for participation in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Standardized uptake value; | — |
Countries
China
Contacts
Public ContactYunlin Feng
Sichuan Academy of Medical Sciences, Sichuan Provincial People's Hospital
Outcome results
None listed