schizophrenia
Conditions
Interventions
Prefrontal lobe treatment group:tACS treatment
Superior temporal gyrus treatment group:tACS treatment
sham:no
Sponsors
Hefei Fourth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for patients with schizophrenia: 1. Aged 18-55 years; 2. Meet the structured clinical diagnostic criteria of DSM-IV and meet the diagnostic criteria for schizophrenia or schizophrenoid disorder; 3. Clinically stable; 4. Discontinue anti-Parkinson's disease drugs 24-48 hours before the experiment; 5. Participants abstained from smoking for 1 h prior to data collection. Inclusion criteria for healthy controls: 1. Aged 18-55 years; 2. Normal visual acuity or corrected vision; 3. Normal hearing; 4. Right-handed; 5. No excessive caffeine, alcohol, nicotine intake.
Exclusion criteria
Exclusion criteria: Exclusion Criteria for patients with schizophrenia: 1. History of cognitive impairment, such as ADHD, mental retardation, cognitive impairment, etc.; 2. History of head trauma, electroconvulsive therapy, syncope and black masking, substance addiction (excluding nicotine addiction); 3. Participants who are currently participating in other experiments are unwilling or unable to complete the entire experiment. Exclusion Criteria for healthy controls: 1. History of cognitive impairment, such as ADHD, mental retardation, cognitive impairment, etc.; 2. Diagnosis of a history of neurological or psychiatric disorders such as obsessive-compulsive disorder, anxiety disorder, personality disorder, etc.; 3. History of mental trauma or head trauma, such as major blows in life, blackness, electroconvulsive therapy, syncope; 4. Have taken drugs or substances that affect the central nervous system, such as antipsychotics, alcohol addiction, tobacco addiction, in the past 2 weeks; 5. Participants who are currently participating in other experiments are unwilling or unable to complete the entire experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| electroencephalogram (EEG);MRI; | — |
Secondary
| Measure | Time frame |
|---|---|
| Positive and negative symptom scales;Concise Psychiatric Rating Scale;Consensus Awareness Scale;Frontal lobe function assessment table; | — |
Countries
China
Contacts
Public ContactWan Li
Hefei Fourth People's Hospital
Outcome results
None listed