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Therapeutic efficacy evaluation of Mirena in CKD patients with AUB

Therapeutic efficacy evaluation of Mirena in CKD patients with AUB

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200065978
Enrollment
Unknown
Registered
2022-11-21
Start date
2022-12-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abnormal Uterine Bleeding

Interventions

Patients having Mirena with AUB after renal transplantation:Place Mirena
Patients having Mirena with CKD + AUB:Place Mirena
Patients having Mirena with AUB and normal renal function:Place Mirena
Patients without AUB after renal transplantation:Place Mirena

Sponsors

The First Affiliated Hospital of Xi'an Jiaotong University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. CKD caused by various causes, regardless of whether patients have undergone renal transplantation; 2. Patients had clinical manifestations such as menorrhagia, prolonged menstruation, irregular vaginal bleeding, endometrial polyps or endometrial thickening, and were willing to place Mirena and able to cooperate with the study, with good compliance. Patients who do not present with these clinical symptoms should have undergone renal transplantation; 3. Agree to participate in this study and sign the informed consent voluntarily.

Exclusion criteria

Exclusion criteria: 1. AUB caused by endometrial dysplasia and higher ranks of lesions, uterine submucosal myoma, cervical cancer, etc.; 2. There are contraindications for placing Mirena; 3. Complicated with major mental diseases, chronic liver diseases, chronic metabolic diseases such as hyperthyroidism, diabetes, etc., and unable to cooperate with treatment.

Design outcomes

Primary

MeasureTime frame
Hemoglobin concentration;Mean Corpuscular Volume;Mean Corpuscular Hemoglobin;Mean Corpusular Hemoglobin Concerntration;Endometrial thickness;Plasma concentration;Serum creatinine;

Countries

China

Contacts

Public ContactQiling Li

The First Affiliated Hospital of Xi'an Jiaotong University

liqiling@mail.xjtu.edu.cn+86 18991232838

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026