cardiovascular disease
Conditions
Interventions
Case series:No intervention was involved in this study
Sponsors
Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Science and Peking Union Medical College
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients who received cardiovascular surgery in Fuwai Hospital from September 1, 2022, to December 31, 2023, with blood loss greater than 500ml in 6 hours after surgery; 2. Patients agde >= 18 years; 3. Patients must meet both cardiovascular surgery and anesthesia criteria and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients were complicated with other heart, lung, and brain diseases, infections, clinically diagnosed severe liver and kidney insufficiency, clinically diagnosed abnormal coagulation function; patients can't cooperate with research, such as language comprehension, mental illness, etc.; 2. Patients whose blood is contaminated by gastrointestinal contents, digestive juices, urine, amniotic fluid, etc.; 3. Patients with sepsis or bacteremia; 4. Patients with malignant tumors whose blood may contain tumor cells; 5. Patients with open thoracic or abdominal injury for more than 4 hours or blood retention in the body cavity for more than 3 days; 6. Other reasons not considered suitable for inclusion in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Erythrocyte recovery and hematocrit; | — |
Secondary
| Measure | Time frame |
|---|---|
| The shape of red blood cells;erythrocyte deformability;Oxygen carrying capacity of red blood cells;Red blood cell surface membrane receptor;Heparin residue;Free hemoglobin concentration;bacterial pollution;inflammatory factor; | — |
Countries
China
Contacts
Public ContactHongwen Ji
Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Science and Peking Union Medical College
Outcome results
None listed