Hepatocellular Carcinoma
Conditions
Interventions
Hepatic vein resection group:Combined hepatic vein resection
Hepatic vein preservation group:Hepatic vein preservation
Sponsors
The First Affiliated Hospital of Guangxi Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 years, hepatitis B virus infection; 2. Patients with hepatectomy combined with hepatic vein resection and patients with hepatectomy combined with hepatic vein preservation; 3. Child Pugh class A liver function, ICG15R <= 10%, Fibro scan liver hardness score <= F3; 4. The preoperative imaging (CT or MRI) examination showed that the distance from the edge of the liver tumor to the hepatic vein <= 1 cm or the hepatic vein was invaded; 5. Postoperative pathological type was hepatocellular carcinoma (HCC).
Exclusion criteria
Exclusion criteria: 1. Pregnancy; 2. History of major abdominal surgery; 3. Multi-organ resection requirements (additional surgery to remove surrounding solid organs); 4. Other hepatitis viruses except hepatitis B or other hepatitis besides hepatitis B at the same time; 5. HCC patients have received interventional and/or chemotherapy and/or radiotherapy and/or targeted immunotherapy and/or microwave ablation and other non surgical resection treatments before surgery; 6. Patients with severe heart, lung, brain dysfunction and/or intolerable surgery; 7. Patients with recurrent and/or metastatic cancer after treatment of hepatocellular carcinoma; 8. Patients with liver tumor invading portal vein at the same time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative functional recovery time;2 year Overall Survival (OS); | — |
Secondary
| Measure | Time frame |
|---|---|
| RFS, recurrence-free survival;the incidence of complications within 30 days after operation;mortality within 90 days after operation; | — |
Countries
China
Contacts
Public ContactZhang Wen
The First Affiliated Hospital of Guangxi Medical University
Outcome results
None listed