Cesarean section undering combined spinal-epidural anesthesia
Conditions
Interventions
Penehyclidine hydrochloride group:received intravenous injection of penehyclidine hydrochloride 0.01 mg/kg 30 min before anesthesia
Normal saline group :received intravenous injection of 1 ml with normal saline 30 min before anesthesia.
Sponsors
Yichang Central People’s Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: The patient that plans to undertake caesarean section operation: 1. Aged 20-40 years; 2. ASA Class I or II; 3. Weight: 50-90 kg; 4. Gestational age: 37-42 weeks.
Exclusion criteria
Exclusion criteria: 1. Anaphylaxis to anticholinergics; 2. Use of analgesics and antiemetic drugs 24 hours before surgery; 3. Patients with a temperature over 38 degree C or symptoms of acute upper respiratory tract infection 24 hours before surgery; 4. Patients with a history of asthma; 5. Patients with pregnancy-related complications such as pregnancy-related hypertension, gestational diabetes mellitus, intrahepatic cholestasis of pregnancy; 6. Patients with mental or neurological disorders or inability to express their wishes correctly; 7. Patients with other conditions that were not considered suitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| non-invasive blood pressure (SBP/DBP);heart rate (HR);Pulse oxygen saturation, SpO2;arterial oxygen pressure;arterial carbon dioxide pressure (PaCO2) ;pulse rate (PR);respiratory rate (RR);the occurrence of dyspnea and other discomfort after delivery;End-expiratory carbon dioxide partial pressure (PetCO2); | — |
Secondary
| Measure | Time frame |
|---|---|
| Apgar scores;umbilical vein pH;partial pressure of oxygen (PO2);the occurrence of shivering during the operation;nausea and vomiting during the operation,; | — |
Countries
China
Contacts
Public ContactGong Yuan
Yichang Central People’s Hospital
Outcome results
None listed