Cervical cancer implantation radiotherapy anesthesia
Conditions
Interventions
Group propofol:propofol 1.5 mg/kg
Group remimazolam 1:remimazolam 0.2 mg/kg
Group remimazolam 2:remimazolam 0.3 mg/kg
Sponsors
Sichuan Cancer Hospital
Eligibility
Sex/Gender
Female
Age
40 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Cervical cancer patients who plan to undergo 3 interstitial brachytherapy; 2. Aged 40-65 years; 3. Weight 50-70 kg; 4. American Society of Anesthesiologists (ASA) grade I-II.
Exclusion criteria
Exclusion criteria: 1. Patients who refuse to participate in the trial; 2. Those with a history of severe heart, brain, lung, liver, kidney and metabolic diseases; 3. Those who have a history of abnormal surgical anesthesia recovery in the past; 4. ECG prompt: heart rate 180 mmHg and/or diastolic blood pressure > 110 mmHg in patients with preoperative hypertension, or < 90/60 mmHg in patients with hypotension; 7. Those who have neuromuscular diseases and mental diseases; 8. Anemia patients; 9. Suspected abuse of narcotic analgesics or sedatives; 10. Those who are predicted to have or have had difficult airway; 11. Those who are known to be allergic to emulsions, benzodiazepines, and opioids; 12. Those who do not cooperate and cannot communicate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood pressure;heart rate;SpO2;Incidence of hypotension;Incidence of hypoxemia;the onset time of sedation;wake up time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Nacrotrend index;observer's assessment of alertness/sedation (OAA/S) score;Injection pain;Intraoperative anesthesia effect;Other related complications; | — |
Countries
China
Contacts
Public ContactJinjun Shu
Sichuan Cancer Hospital
Outcome results
None listed