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Effect of routine hysteroscopy before IVF/ICSI on live birth rate in infertile women with normal uterine cavity by ultrasound: a multicenter randomized clinical trial

Effect of routine hysteroscopy before IVF/ICSI on live birth rate in infertile women with normal uterine cavity by ultrasound: a multicenter randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200065927
Enrollment
Unknown
Registered
2022-11-18
Start date
2024-03-26
Completion date
Unknown
Last updated
2026-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometrial Diseases

Interventions

Group A :Perform Hysteroscopy
Group B:Without Hysteroscopy

Sponsors

Reproductive Hospital Affiliated to Shandong University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 38 Years

Inclusion criteria

Inclusion criteria: 1. Infertility; 2. IVF/ICSI assisted fertility treatment is planned for the first time; 3. Aged 20-38 years; 4. Accept and adhere to treatment and follow-up.

Exclusion criteria

Exclusion criteria: 1. Suffer from hysteroscopic surgery contraindications; 2. During follicular phase, 3D/2D or water injection ultrasound >= 2 times indicates visible lesions in uterine cavity, including uterine cavity adhesion, submucous myoma, hyperechoic light mass, mediastinum, etc; 3. Untreated hydrosalpinx; 4. Two or more miscarriages missed before 20 weeks of gestation; 5. Abnormal number or structure of chromosomes or mutations of pathogenic genes in one spouse; 6. Fibroids greater than 4 cm in diameter; 7. Abnormal uterine bleeding; 8. Egg donors.

Design outcomes

Primary

MeasureTime frame
live birth rate;

Secondary

MeasureTime frame
Complications of hysteroscopy and surgery;Pain score of operation;Comfort tolerance after operation;miscarriage rate;Ectopic pregnancy rate;Incidence of maternal complications during pregnancy;Incidence of neonatal complications;Cost of hysteroscopy;Cost of in vitro fertilization (IVF) treatment;

Countries

China

Contacts

Public ContactLei Yan

Reproductive Hospital Affiliated to Shandong University

yanlei@sdu.edu.cn+86 186 6078 2393

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 25, 2026