Solid tumors and hematological tumors
Conditions
Interventions
imaging
pathological puncture biopsy
surgery
Index test:PET/CT, SUVmax, TBR
Sponsors
The Affiliated Hospital of Southwest Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-75 years, male or female, ECOG score 0 or 1 (see Annex 1 for the score sheet); 2. Subjects with recent (within 2 months) proposed pathological tissue biopsy or surgical oncology treatment for head and neck tumor, lung cancer, esophageal cancer, breast cancer, ovarian cancer, liver cancer, bile duct cancer, colorectal cancer, gastric cancer, pancreatic cancer, melanoma, bone tumor, renal clear cell carcinoma, hematologic tumor subjects or subjects with suspected tumor; 3. Expected survival >= 12 weeks; 4. Rutine blood, liver and kidney function to meet the following criteria: routine blood: WBC >= 4.0 x 10^9/L or neutrophils >= 1.5 x 10^9/L, PLT >=100 x 10^9/LL, Hb >= 90 g/L; PT or APTT <= 1.5 ULN; liver and kidney function: T-Bil <= 1.5 x ULT (upper limit of normal), ALT/AST <= 2.5 ULN or <= 5 x ULT (for subjects with liver metastases), ALP <= 2.5 ULN (if bone metastases or liver metastases ALP <= 4.5 ULN are present); BUN <= 1.5 x ULT, SCr <= 1.5 x ULT; 5. Presence of at least one measurable target lesion according to RECIST 1.1 criteria; 6. Females who must use effective contraception during the study and for 6 months after the end of the study period (effective contraception is defined as sterilization, intrauterine hormonal device, condoms, contraceptive pills/drugs, abstinence or partner vasectomy, etc.); males should agree to be subjects who must use contraception during the study and for 6 months after the end of the study period; 7. Ability to understand and voluntarily sign the informed consent form and good compliance.
Exclusion criteria
Exclusion criteria: 1. Severe abnormalities in heart, liver and kidney function; 2. Women who are preparing for pregnancy, pregnant and breastfeeding; 3. Those who are unable to lie flat for half an hour; 4. Those who suffer from claustrophobia or other psychiatric disorders; 5. Any other condition that the investigator considers unsuitable for participation in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SUVmax, Standardized Uptake Value Maximum;Adverse reactions;TBR, target background ratio;sensitivity;Specificity; | — |
Countries
China
Contacts
Public ContactCai Liang
The Affiliated Hospital of Southwest Medical University
Outcome results
None listed