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The Research of the Clinical Effect of Platelet-Rich Fibrin in Immediate Implant of Infected Posterior Teeth

The Research of the Clinical Effect of Platelet-Rich Fibrin in Immediate Implant of Infected Posterior Teeth

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200065888
Enrollment
Unknown
Registered
2022-11-17
Start date
2022-12-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

immediate implant

Interventions

Sponsors

Hospital of Stomatology, Jilin University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. The residual bone tissue at the root tip was not less than 3mm, which had good primary stability; 2. The remaining bone wall of the extraction socket was four-walled bone; 3. The keratinized gingiva was the thick gingival biotype; 4. Smoking 18 years old.

Exclusion criteria

Exclusion criteria: 1. Obvious bone fenestration or dehiscence on the buccal side of the extraction socket; 2. The remaining bone wall of the extraction socket was one-walled, two-walled, or three-walled; 3. Severe deep overbite and night bruxism; 4. Acute suppurative inflammation of alveolar fossa and discharge of purulent fistula after tooth extraction; 5. Diabetic patients with fasting blood glucose > 8.88 mmol/L; 6. Hypertensive patients with diastolic blood pressure > 90 mmHg; 7. Patients taking corticosteroids for systemic diseases; 8. Patients with recent use of anticoagulant drugs such as warfarin or coagulation disorders; 9. Patients with severe osteoporosis and patients with intravenous bisphosphonates and other anti-osteoporosis drugs; 10. Patients treated with head and neck radiotherapy within the past three years; 11. Patients with recent myocardial infarction and cardiac stent implantation; 12. Patients with severe mental illness unable to cooperate with treatment or unable to follow up regularly.

Design outcomes

Primary

MeasureTime frame
Height of the buccolingual bone;Buccal bone thickness;

Secondary

MeasureTime frame
Width of alveolar socket;Peri-implant bone volume;Peri-implant bone mineral density;Soft tissue evaluation of implants;Pink aesthetic rating;White aesthetic rating;Keratinized gingival changes;Stability of implant;Implant survival rate;The incidence of peri-implantitis and peri-implantitis mucositis;

Countries

China

Contacts

Public ContactZhou Yanmin

Hospital of Stomatology, Jilin University

zhouym62@126.com+86 18943971001

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026