Effect of driving pressure guided individualized PEEP on pulmonary function and postoperative pulmonary complications in patients undergoing retroperitoneal laparoscopic surgery

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200065879

Enrollment

Unknown

Registered

2022-11-17

Start date

2022-12-01

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intraoperative pulmonary function and postoperative pulmonary complications

Interventions

experimential group:Individualized PEEP

control group:Fixed PEEP

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing retroperitoneal laparoscopic surgery are expected to have a pneumoperitoneum duration of 1-3 hours; 2. Age: 18 to 65 years old; 3. The ASA classification is I-III; 4. BMI < 30 kg/m2.

Exclusion criteria

Exclusion criteria: 1. Severe pulmonary diseases, such as chronic obstructive pulmonary disease, asthma, pleural effusion, pneumothorax, pulmonary bullae, etc.; 2. Respiratory tract infection within 14 days; 3. History of pulmonary surgery; 4. Quit smoking for less than 14 days; 5. Have received invasive mechanical ventilation within 30 days; 6. Spinal or thoracic deformity; 7. Severe heart disease (heart failure, acute coronary syndrome, severe arrhythmia).

Design outcomes

Primary

Measure	Time frame
Oxygenation index;	—

Secondary

Measure	Time frame
Driving pressure;Lung dynamic compliance;Lung static compliance;Incidence of postoperative pulmonary complications;Alveolar-arterial oxygen difference;VD/VT;	—

Countries

China

Contacts

Public ContactWang Guanglei

Department of Anesthesiology, The Affiliated Hospital of Xuzhou Medical University

13852087156@163.com+86 13852087156

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026