Anesthesia induction
Conditions
Interventions
Prop-2.5:Propofol 2.5 mg/kg
Fosp-10.0:Fospropofol 10.0 mg/kg
Fosp-15.0:Fospropofol 15.0 mg/kg
Fosp-20.0:Fospropofol 20.0 mg/kg
Fosp-25.0:Fospropofol 25.0 mg/kg
Sponsors
The First Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients who plan to undergo elective surgery under general anesthesia; 2. Aged 18-75 years old, gender unlimited; 3. Body mass index (BMI) 18.5~30 kg/m2; 4. ASA was graded from I to III.
Exclusion criteria
Exclusion criteria: 1. The patient was complicated with cardiopulmonary and cerebral diseases; 2. Patients with liver or kidney insufficiency; 3. Those who are predicted to have or have had difficulty airway; 4. Patients with previous bradycardia or arrhythmia; 5. Preoperative severe hypertension (>180/110mmHg) or hypotension (<90/60mmHg); 6. Patients with anemia or coagulation disorders; 7. Patients with neuromuscular system diseases or mental diseases; 8. Suspected abuse of narcotic analgesics or sedatives; 9. The patient's history of food or drug allergy; 10. Patients with chronic smoking or alcohol abuse and other bad habits.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Onset time;Injection pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sedation;Vital signs; | — |
Countries
China
Contacts
Public ContactJin Xin
The First Affiliated Hospital of Soochow University
Outcome results
None listed