Breast diseases
Conditions
Interventions
Experimental group: Sedline monitoring:Maintain BIS at an appropriate depth of anesthesia with appropriate medication to observe changes in Sedline
Control group:Experience anesthesia, without intervention while observing Sedline changes
Sponsors
The Fourth Affiliated Hospital of Harbin Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Breast surgery, including breast cancer and benign breast tumors, was discussed and agreed by the group of general surgery experts; 2. Observers ( or representatives of patients ) voluntarily participate in and sign informed consent; 3. Aged 18-75 years of age; 4. ASA grade I-III.
Exclusion criteria
Exclusion criteria: 1. The observers (or their legal representatives) are unwilling to sign the informed consent; 2. Patients with poor compliance (including economic status); 3. With severe cardiovascular disease history, diabetes, severe infection; 4. Related drug allergy history and taboo; 5. Maternity of pregnant women; 6. Other factors that may affect patient inclusion and assessment results.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative sedation depth of patients; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pupil diameter at entry;Pupil diameter at loss of consciousness;Pupil diameter after intubation;Pupil diameter 30 minutes after surgery begins;Pupil diameter before extubation;Pupil diameter before extubation;Pupil diameter before exit;Continuous variable statistics of BIS values;Continuous Variable Statistics of BIS Spectral Margin Frequency;Continuous variable statistics of PSI;Continuous variable statistics of Sedline spectral edge frequency; | — |
Countries
China
Contacts
Public ContactWei Yu
The Fourth Affiliated Hospital of Harbin Medical University
Outcome results
None listed