stroke
Conditions
Interventions
control group:conventional therapy
experimental group1:MI-BCI + conventional therapy
experimental group1:rTMS + conventional therapy
experimental group3:MI-BCI + rTMS + conventional therapy
Sponsors
Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18~75 years; 2. Meet the stroke diagnosis criteria formulated by the Fourth National Academic Conference on Cerebrovascular Diseases in 1995; 3. First stroke and unilateral hemiplegia, 4 weeks-6 months; 4. With moderate and severe hand dysfunction (2 <= Brunnstrom <= 4), modified Ashworth spasm scale (MAS) <3; 5. Voluntarily participate in and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with limb dysfunction resulting from other causes before disease onset; 2. Patients with severe cardiopulmonary and kidney diseases and mental disorders; 3. Patients with other neurological diseases, no training or poor treatment compliance; 4. Patients with cognitive understanding dysfunction: Mini-mental State Examination (MMSE) <= 17 points, visual or auditory impairment; 5. Patients with speech impairment who can't cooperated; 6. Patients with unstable fracture, infection, and active bleeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fugl Meyer assessment of motor function;The WMFT score of the upper extremity;fMRI;Near-infrared functional brain imaging; | — |
Secondary
| Measure | Time frame |
|---|---|
| Modified Barthel index;Brunnstrom stage; | — |
Countries
China
Contacts
Public ContactXu Li
Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China
Outcome results
None listed