Pressure ulcer
Conditions
Interventions
PRP group:Packed gauze soaked with PRP preparation after washing with normal saline
CGF group:After washing with normal saline, the gauze soaked in CGF preparation shall be filled
Tideglusib group:Skin tissue culture with Tideglusib treatment in vitro
Control group:Covered with oil yarn after washing with normal saline
Sponsors
Department of Burns and Plastic Surgery, the Fourth Medical Center of Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. The patient was diagnosed as stage 3-4 pressure ulcer; 2. Patients with pressure ulcers who have been treated for more than 1 month and have not healed; 3. Having a life expectancy of at least 6 months, and can follow up the safety and effectiveness data; 4. The patient aged > 18 years.
Exclusion criteria
Exclusion criteria: 1. Patients with ulcers caused by other reasons; 2. HIV positive patients; 3. Patients with autoimmune diseases; 4. Patients suffering from malignant tumors; 5. Patients with major organic diseases or serious heart and lung diseases can not tolerate debridement; 6. Allergies to blood products; 7. Thrombocytopenia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wound area; | — |
Secondary
| Measure | Time frame |
|---|---|
| growth factor concentration;Inflammation level; | — |
Countries
China
Contacts
Public ContactChuan'an Shen
The Fourth Medical Center of Chinese PLA General Hospital
Outcome results
None listed