propofol-induced injection pain
Conditions
Interventions
S:Pretreating normal saline 30 seconds before propofol injection
R:Pretreating remimazolam 30 seconds before propofol injection
L:Pretreating lidocaine 30 seconds before propofol injection
E:Pretreating esketamine 30 seconds before propofol injection
Sponsors
Jinan Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients (ASA I ~II, aged 18-65 years, BMI 18~28 kg/m2) undergone selective gastroscopy.
Exclusion criteria
Exclusion criteria: 1. Patients with upper respiratory tract infection and asthma recently; 2. Those who are allergic to experimental drugs; 3. Those with severe risk of elevated blood pressure or intracranial pressure; 4. Hypertension (blood pressure at rest > 170/100); 5. Hyperthyroidism; 6. Serious insufficiency of important organs; 7. Patients with obvious ischemic heart disease; 8. Sinus tachycardia; 9. Abuse of alcohol or analgesic, sedative, antidepressant drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of propofol-induced injection pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| the intensity of propofol-induced injection pain;blood pressure;heart rate;SpO2;satisfaction of people;adverse events; | — |
Countries
China
Contacts
Public ContactYuan Ruimei
Jinan Central Hospital; Central Hospital Affiliated to Shandong First Medical University
Outcome results
None listed