Helicobacter pylori
Conditions
Interventions
Experimental group 1:High dose Amoxicillin + Vonoprazan
Experimental group 2:Amoxicillin + Vonoprazan + Saccharomyces boulardii
Sponsors
The Affiliated Changzhou Second People's Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Age
17 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-70 years old, male or female; 2. No antibiotics, bismuth, H2 receptor antagonists or proton pump inhibitors were used in the last four weeks; 3. 13C urea breath test or rapid urease test positive; 4. Have indications of Helicobacter pylori eradication treatment and are willing to cooperate with the doctor to conduct a follow-up investigation of the eradication effect.
Exclusion criteria
Exclusion criteria: 1. Severe heart, liver and kidney damage; 2. Pregnant or lactating women; 3. Previous history of upper digestive tract surgery, gastric malignancy, liver and kidney function damage, pyloric stenosis, pregnancy, etc.; 4. Patients taking NSAIDS or drinking alcohol at the same time; 5. Patients who are allergic to any drug of the eradication program.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eradication rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Compliance;Adverse Events; | — |
Countries
China
Contacts
Public ContactXiaoyong Wang
The Affiliated Changzhou Second People's Hospital of Nanjing Medical University
Outcome results
None listed