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Functional near-infrared spectroscopy (fNIRS) was used to study brain activity during action observation and mirror therapy in stroke patients

Functional near-infrared spectroscopy (fNIRS) was used to study brain activity during action observation and mirror therapy in stroke patients

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200065838
Enrollment
Unknown
Registered
2022-11-16
Start date
2022-11-21
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

AOT1:action observation
AOT2:action observation plus imagination
AOT3:action observation plus execution
AOT4:action observation plus imagination and execution
MT1:mirror therapy
MT2:mirror therapy plus imagination
MT3:mirror therapy plus execution
MT4:mirror therapy plus imagination and execution

Sponsors

Sichuan Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. The patient was diagnosed as ischemic stroke by cranial CT or MRI, and the patient was diagnosed as ischemic stroke by first onset, with only one hemisphere injury, meeting the diagnostic criteria of the Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke formulated by the Neurology Branch of the Chinese Medical Association in 2014; 2. During the study period, his condition was stable and his consciousness and consciousness were clear; 3. At the time of enrollment, the patients' sitting balance was greater than grade I, the lower extremity muscle tone was rated as modified Ashworth grade <= grade 2, and the lower extremity Brunnstorm stage was I ~ IV; 4. The score of Mini-mental state examination (MMSE) was more than 24, and there was no obvious cognitive dysfunction; 5. No diseases that can cause brain function changes, such as head trauma, intracranial infection, multiple sclerosis, etc.; 6. After the investigation of Chinese handedness criteria, it is judged to be right handedness; 7. The patient himself or his family members sign the informed consent voluntarily.

Exclusion criteria

Exclusion criteria: 1. Unstable vital signs; 2. Intracranial organic lesions (space occupation, vascular malformation, infection, trauma, congenital developmental abnormalities); 3. Cognitive dysfunction, mental disorders and incompatibility; 4. Patients with visual spatial impairment; 5. There are metal foreign bodies in the body or other conditions not suitable for MRI examination; 6. Previous history of stroke, epilepsy, dementia, depression history.

Design outcomes

Primary

MeasureTime frame
HbO2;

Countries

China

Contacts

Public ContactLi Xu

Sichuan Provincial People's Hospital

xuli_0125@163.com+86 18908010201

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026