Intestinal diseases
Conditions
Interventions
Experimental group 1:The day before colonoscopy, 290ug linalotide was taken orally before lunch/dinner, and 2L PEG was taken orally 4~6 hours before the operation on the same day
Experimental group 2:Oral administration of 580ug linaclotide before dinner the day before colonoscopy, and oral administration of 2L PEG 4~6 hours before the procedure on the same day
Control group:Take 1L PEG orally the night before colonoscopy, and 2L PEG 4~6 hours before the same-day operation
Sponsors
General Hospital of the Northern Theater of the Chinese People's Liberation Army
Eligibility
Sex/Gender
All
Age
19 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Aged >= 19 years old, male or female; 2. Be able to understand the procedures and methods of this study, be willing to sign the informed consent form and strictly abide by the clinical research protocol to complete the study.
Exclusion criteria
Exclusion criteria: 1. Known or suspected allergy to colon cleansing drug ingredients; 2. Suspicious or definite mechanical intestinal obstruction, perforation, toxic megacolon, intestinal foreign body; 3. After colon surgery; 4. Patients with active inflammatory bowel disease or diverticulitis; 5. Heart failure (NYHA grade III to IV), kidney failure, liver failure; 6. Pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Boston bowel preparation score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Polyp detection rate (PDR) and adenoma detection rate (ADR) of the entire colon, calculated as the percentage of patients with at least one polyp (PDR) or adenoma (ADR), cecal intubation rate;Tolerance and safety; | — |
Countries
China
Contacts
Public ContactYang Zhuo
General Hospital of the Northern Theater of the Chinese People's Liberation Army
Outcome results
None listed