minimal hepatic encephalopathy
Conditions
Interventions
Gold Standard:Psychometric hepatic encephalopathy score (PHES)
Index test:Gut microbiota
Metabolites of gut microbiota
Sponsors
People's Hospital of Ningxia Hui Autonomous Region
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Adult patients with hepatitis B-related liver cirrhosis diagnosed according to the Guidelines for the Prevention and Treatment of Chronic Hepatitis B (2019 edition); 2. Subjects have normal reading and cognitive abilities, and are able to independently complete the psychometric hepatic encephalopathy score(PHES) testing; 3. Subjects have agreed to participate in this study.
Exclusion criteria
Exclusion criteria: 1. Diagnosed as overt hepatic encephalopathy according to the Guidelines for Diagnosis and Treatment of Hepatic Encephalopathy in Liver Cirrhosis (2018 edition); 2. With mental or nervous system diseases; 3. Taking sedatives or central nervous system inhibitors within the last one month; 4. Alcoholic cirrhosis, hepatocellular carcinoma or other malignancies; 5. Gastrointestinal bleeding and water, electrolyte, acid-base imbalance within the last one month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Metabolites of gut microbiota;ROC curve;sensitivity;Specificity;positive predictive value;negative predictive value;Accuracy; | — |
Countries
China
Contacts
Public ContactFeihu Bai
People's Hospital of Ningxia Hui Autonomous Region
Outcome results
None listed