ischemic heart disease
Conditions
Interventions
Remimazolam Group:Remimazolam 0.2 mg/kg IV bolus
Control group:Conventional general anesthesia with propofol
Sponsors
The First Affiliated Hospital of Guangxi Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria of ischemic heart disease, and the condition is stable; Ischemic heart disease includes the following clinical types: (1) Arteriosclerotic heart disease; (2) Stable angina pectoris; (3) Old myocardial infarction: myocardial infarction diagnosed by electrocardiogram or other special examination in the past, but no symptoms in the near future; (4) Cardiac aneurysm; (5) Coronary artery aneurysm: coronary artery arteriovenous fistula, acquired. Excludes: Congenital coronary (arterial) aneurysm (Q24.5); (6) Ischemic cardiomyopathy; (7) Silent myocardial ischemia; 2. All patients underwent elective non-cardiac surgery under general anesthesia; 3. United States Society of Anesthesiologists (ASA) classification <= III, and new York Heart Association (NYHA) classification <= II; 4. There were no serious lesions of heart, lung, brain and other important organs before operation, and no obvious abnormality of liver and kidney function; 5. Clearly understand the study content and voluntarily participate in the study before operation, and sign the informed consent form for the study.
Exclusion criteria
Exclusion criteria: 1. Patients with recent (within 6 months) aggravated heart disease; 2. Cardiac dysplasia; 3. Severe infection, shock or dysfunction of important organs; 4. Preoperative state of consciousness, mental state and central nervous system disorders; 5. Severe arrhythmia and anemia (Hb <= 60g/L) before operation; 6. History of severe allergy to the study drug.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Myocardial injury markers; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemoglobin;Visual Analogue Score; | — |
Countries
China
Contacts
Public ContactChen Yanhua
The First Affiliated Hospital of Guangxi Medical University
Outcome results
None listed