Correlation between changes of cranial MRI and postoperative cognitive impairment in elderly patients undergoing total hip arthroplasty

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200065818

Enrollment

Unknown

Registered

2022-11-16

Start date

2022-11-16

Completion date

Unknown

Last updated

2023-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perioperative cognitive dysfunction

Interventions

control group:No

GOPD group:N/A

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged > 60 years; 2. It is planned to perform total hip replacement under general anesthesia; 3. There was no surgical treatment for other surgical system diseases nearly one month before admission.

Exclusion criteria

Exclusion criteria: 1. Pathological fracture and multiple fracture; 2. Mini mental state examination (MMSE) score 9; 3. Patients with central nervous system disease or severe craniocerebral trauma and thoracoabdominal trauma; 4. Those who cannot complete cognitive function test or have received neuropsychological test; 5. Taking sedatives or antidepressants; 6. Have received nerve or heart surgery; 7. Not willing to follow the rules or procedures or unable to understand and communicate; 8. Illiteracy or serious visual or hearing impairment; 9. Parkinson's disease; 10. Alcohol abuse or drug dependence;

Design outcomes

Primary

Measure	Time frame
Mini-mental State Examination;Head MRI;General information of the patient;Intraoperative circulation and medication;	—

Countries

China

Contacts

Public ContactJiang Yage

The First Affiliated Hospital of Guangxi Medical University

904226223@qq.com+86 15289685261

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026