Effect of mandibular third molar extraction on periodental microbiota and clinical parameters of adjacent teeth: a prospective controlled trial

Status

Active, not recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200065817

Enrollment

Unknown

Registered

2022-11-16

Start date

2022-11-27

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

periodontal disease

Interventions

Envelope flap group:Envelope incision

Triangular flap group:Trianguler incision

Modified triangular flap group:Modified triangular incision

Eligibility

Sex/Gender

All

Age

18 Years to 25 Years

Inclusion criteria

Inclusion criteria: 1. The patient's whole body is healthy, all the extracted impacted mandibular third molars are completely submucosal impacted, and the impacted mandibular third molar and adjacent second molar have no local inflammation and no blind pocket; 2. According to the panoramic X-ray film, patients with BII class mesial or horizontal IMTMs with similar technical difficulty were selected; 3. The distance from the most convex point of the crown of the impacted mandibular third molar to the most concave point of the distal neck of the adjacent second molar (i.e. the wisdom tooth) Anterior space) is 0mm, and the distal alveolar ridge of the adjacent second molar is 4-5mm away from the enamel-alveolar bone junction; 4. The impacted mandibular third molar and adjacent second molar do not have any local inflammation or other Lesion; 5. The second molar is located in the dental arch and is vertical, the third molar is located in the distal part of the second molar, and the angle between the jaw plane and the mandibular plane of the impacted mandibular third molar is 11°-100°.

Exclusion criteria

Exclusion criteria: 1. Intraoperative debridement and operative time > 45min; 2. Those on post-operative antibiotics and mouthwash; 3. Patients with concomitant jaw fractures/chronic systemic illness; 4. The habit of smoking; 5. Pregnancy; 6. Patients with chronic periodontal disease; 7. Patients on steroids or non-steroidal anti-inflammatory drugs, probiotics, antibiotics and bisphosphonates within the past 90 days preoperatively; 8. Patients with a cyst or tumor of the jaw.

Design outcomes

Primary

Measure	Time frame
Probing depth;microbial diversity;Microbial composition;	—

Secondary

Measure	Time frame
attachment loss;Plaque Index;Bleeding on probing;	—

Countries

China

Contacts

Public ContactXing Wang

Shanxi Medical University School and Hospital of Stomatology

wangxing@sxmu.edu.cn+86 13934224604

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026