Chronic cough after lung cancer surgery
Conditions
Interventions
A:cutting the most caudal lung branch nerve and filled the residual cavity after lymph node dissection using absorbable hemostatic yarn
B:preserved the most caudal lung branch nerve and filled the residual cavity after lymph node dissection using absorbable hemostatic yarn
C:cutting the most caudal lung branch nerve and not filled the residual cavity after lymph node dissection using absorbable hemostatic yarn
D:preserved the most caudal lung branch nerve and not filled the residual cavity after lymph node dissection using absorbable hemostatic yarn
Sponsors
The Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. ASA grade I-III; 2. Aged >= 18 years, male and female is unlimited; 3. Adult patients with elective thoracoscopic lobectomy and lymphadenectomy; and preoperative imaging findings of peripheral bronchopulmonary cancer, maximum diameter of <= 5cm (T<=2), no regional lymph node involvement (N0) or ipsilateral peribronchial lymph nodes and ipsilateral hilar lymph node involvement (N1), no evidence of distant metastasis (M0); 4. Consent was to participate in this study and signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. History of chronic cough, such as chronic bronchitis, asthma, gastroesophageal reflux disease, and retronasal drip syndrome; 2. Use of an angiotensin-converting enzyme inhibitor (ACEI); 3. Severe arrhythmia; 4. Previous history of thoracic surgery; 5. Simple lung wedge resection or lobectomy combined with a wedge resection is required; 6. See obvious chest adhesion during surgery; (Note: the adhesion area exceeds a single lung lobe or the cumulative adhesion area reaches 30% or more of the lung surface area); 7. Patients undergoing preoperative neoadjuvant therapy; 8. Preoperative chest CT measurements were the mediastinal lymph nodes greater than 10mm; 9. Previous history of tuberculosis or tuberculous pleurisy; 10. The intraoperative rapid freezing pathology reported the results as benign.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of chronic cough; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of cough;Pulmonary function index;postoperative complications ;Tumor classification and stage, and the number and size of dissected lymph nodes in the pathological results;cough CSS score;Visual Analogu Scale score;LCQ-MC score; | — |
Countries
China
Contacts
Public ContactHao Zhang
The Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed