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Application of three-dimensional image reconstruction in evaluation of the effect of immunotherapy combined with neoadjuvant chemotherapy in patients with esophageal squamous cell carcinoma

Application of three-dimensional image reconstruction in evaluation of the effect of immunotherapy combined with neoadjuvant chemotherapy in patients with esophageal squamous cell carcinoma

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200065801
Enrollment
Unknown
Registered
2022-11-15
Start date
2022-10-09
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal squamous cell carcinoma

Interventions

Observation Group:None

Sponsors

Department of Thoracic Surgery, Army Specialized Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 77 Years

Inclusion criteria

Inclusion criteria: 1. Patients with locally advanced-locally advanced esophageal cancer (stage T2-4N0-2M0 before treatment) were not enrolled in other clinical trials; 2. Two cycles of neoadjuvant therapy (immunotherapy plus chemotherapy) were performed regularly in the study center; 3. There were complete chest CT images before and after neoadjuvant therapy; 4. Esophageal carcinoma was treated with minimaly invasive esophagectomy, the resection were subjected to pathological biopsy; 5. Cooperate with follow-up and inspection; 6. Patients are able to sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients who died during hospitalization; 2. The patients with an adenocarcinoma of esophago-gastric junction; 3. Patients without complete CT imaging data.

Design outcomes

Primary

MeasureTime frame
Tumor volume;

Secondary

MeasureTime frame
Pathologic staging and grading;tumor regression grade;

Countries

China

Contacts

Public ContactGuo Wei

Army Specialized Medical Center (Daping Hospital)

gyguowei@hotmail.com+86 13527323568

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026